{ "data_id": "27205", "name": "QSAR-DATASET-FOR-DRUG-TARGET-CHEMBL285", "exact_name": "QSAR-DATASET-FOR-DRUG-TARGET-CHEMBL285", "version": 8, "version_label": null, "description": "This dataset contains QSAR data (from ChEMBL version 17) showing activity values (unit is pseudo-pCI50) of several compounds on drug target ChEMBL_ID: CHEMBL285 (TID: 11203), and it has 721 rows and 43 features (not including molecule IDs and class feature: molecule_id and pXC50). The features represent Basic Molecular Descriptors which were generated from SMILES strings. Missing value imputation was applied to this dataset (By choosing the Median).", "format": "ARFF", "uploader": "Noureddin Sadawi", "uploader_id": 62, "visibility": "public", "creator": "\"Dr Jeremy Besnard, Dr Ivan Olier, Dr Noureddin Sadawi, Dr Larisa Soldatova, Dr Crina Grosan, Prof Ross King, Dr Richard Bickerton, Prof Andrew Hopkins and Dr Willem van Hoorn\"", "contributor": null, "date": "2016-07-14 21:01:53", "update_comment": null, "last_update": "2016-07-14 21:01:53", "licence": "Public", "status": "deactivated", "error_message": null, "url": "https:\/\/www.openml.org\/data\/download\/3323718\/data_34521.arff", "default_target_attribute": "pXC50", "row_id_attribute": "molecule_id", "ignore_attribute": null, "runs": 1, "suggest": { "input": [ "QSAR-DATASET-FOR-DRUG-TARGET-CHEMBL285", "This dataset contains QSAR data (from ChEMBL version 17) showing activity values (unit is pseudo-pCI50) of several compounds on drug target ChEMBL_ID: CHEMBL285 (TID: 11203), and it has 721 rows and 43 features (not including molecule IDs and class feature: molecule_id and pXC50). The features represent Basic Molecular Descriptors which were generated from SMILES strings. Missing value imputation was applied to this dataset (By choosing the Median). " ], "weight": 5 }, "qualities": { "NumberOfInstances": 721, "NumberOfFeatures": 45, "NumberOfClasses": 0, "NumberOfMissingValues": 0, "NumberOfInstancesWithMissingValues": 0, "NumberOfNumericFeatures": 44, "NumberOfSymbolicFeatures": 1, "MeanAttributeEntropy": null, "MinorityClassSize": null, "Quartile1MeansOfNumericAtts": 0.5110957004160869, "StdvNominalAttDistinctValues": null, "MeanKurtosisOfNumericAtts": 25.062255673070894, "NumberOfBinaryFeatures": 0, "Quartile1MutualInformation": null, "MeanMeansOfNumericAtts": 28.874817898121297, "Quartile1SkewnessOfNumericAtts": -0.1466414627867203, "MeanMutualInformation": null, "Quartile1StdDevOfNumericAtts": 0.11299720416247874, "AutoCorrelation": 0.07475000000000086, "MeanNoiseToSignalRatio": null, "Quartile2AttributeEntropy": null, "ClassEntropy": null, "MeanNominalAttDistinctValues": null, "Quartile2KurtosisOfNumericAtts": -0.1292609019764086, "Dimensionality": 0.06241331484049931, "MeanSkewnessOfNumericAtts": 1.8599448656414486, "Quartile2MeansOfNumericAtts": 5.258296116504854, "EquivalentNumberOfAtts": null, "MeanStdDevOfNumericAtts": 5.724732904760847, "Quartile2MutualInformation": null, "MajorityClassPercentage": null, "MinAttributeEntropy": null, "Quartile2SkewnessOfNumericAtts": 0.1710337347477303, "MajorityClassSize": null, "MinKurtosisOfNumericAtts": -1.1635575914559475, "PercentageOfBinaryFeatures": 0, "Quartile2StdDevOfNumericAtts": 2.048157559466143, "MaxAttributeEntropy": null, "MaxKurtosisOfNumericAtts": 357.9888618290352, "MinMeansOfNumericAtts": 0, "PercentageOfInstancesWithMissingValues": 0, "Quartile3AttributeEntropy": null, "MaxMeansOfNumericAtts": 491.1814979195562, "MinMutualInformation": null, "PercentageOfMissingValues": 0, "Quartile3KurtosisOfNumericAtts": 1.9343300216519812, "MaxMutualInformation": null, "MinNominalAttDistinctValues": null, "PercentageOfNumericFeatures": 97.77777777777777, "Quartile3MeansOfNumericAtts": 37.25693481276006, "MaxNominalAttDistinctValues": null, "MinSkewnessOfNumericAtts": -0.8323437171151616, "PercentageOfSymbolicFeatures": 2.2222222222222223, "Quartile3MutualInformation": null, "MaxSkewnessOfNumericAtts": 18.947185316499464, "MinStdDevOfNumericAtts": 0, "Quartile1AttributeEntropy": null, "Quartile3SkewnessOfNumericAtts": 1.1507492788822398, "MaxStdDevOfNumericAtts": 83.03804860977765, "MinorityClassPercentage": null, "Quartile1KurtosisOfNumericAtts": -0.5539207516443216, "Quartile3StdDevOfNumericAtts": 6.347213403417393 }, "tags": [ { "tag": "MetaQSAR", "uploader": "62" }, { "tag": "study_13", "uploader": "62" } ], "features": [ { "name": "pXC50", "index": "44", "type": "numeric", "distinct": "314", "missing": "0", "target": "1", "min": "4", "max": "8", "mean": "6", "stdev": "1" }, { "name": "molecule_id", "index": "0", "type": "nominal", "distinct": "721", "missing": "0", "identifier": "1", "distr": [] }, { "name": "AMW", "index": "1", "type": "numeric", "distinct": "465", "missing": "0", "min": "5", "max": "10", "mean": "7", "stdev": "1" }, { "name": "C.", "index": "2", "type": "numeric", "distinct": "142", "missing": "0", "min": "31", "max": "54", "mean": "40", "stdev": "5" }, { "name": "H.", "index": "3", "type": "numeric", "distinct": "171", "missing": "0", "min": "30", "max": "61", "mean": "51", "stdev": "5" }, { "name": "Me", "index": "4", "type": "numeric", "distinct": "60", "missing": "0", "min": "1", "max": "1", "mean": "1", "stdev": "0" }, { "name": "Mi", "index": "5", "type": "numeric", "distinct": "50", "missing": "0", "min": "1", "max": "1", "mean": "1", "stdev": "0" }, { "name": "Mp", "index": "6", "type": "numeric", "distinct": "118", "missing": "0", "min": "1", "max": "1", "mean": "1", "stdev": "0" }, { "name": "Mv", "index": "7", "type": "numeric", "distinct": "135", "missing": "0", "min": "1", "max": "1", "mean": "1", "stdev": "0" }, { "name": "MW", "index": "8", "type": "numeric", "distinct": "515", "missing": "0", "min": "250", "max": "747", "mean": "491", "stdev": "83" }, { "name": "N.", "index": "9", "type": "numeric", "distinct": "78", "missing": "0", "min": "0", "max": "11", "mean": "4", "stdev": "2" }, { "name": "nAB", "index": "10", "type": "numeric", "distinct": "12", "missing": "0", "min": "0", "max": "29", "mean": "15", "stdev": "6" }, { "name": "nAT", "index": "11", "type": "numeric", "distinct": "71", "missing": "0", "min": "28", "max": "113", "mean": "72", "stdev": "14" }, { "name": "nB", "index": "12", "type": "numeric", "distinct": "1", "missing": "0", "min": "0", "max": "0", "mean": "0", "stdev": "0" }, { "name": "nBM", "index": "13", "type": "numeric", "distinct": "27", "missing": "0", "min": "0", "max": "30", "mean": "17", "stdev": "6" }, { "name": "nBO", "index": "14", "type": "numeric", "distinct": "34", "missing": "0", "min": "21", "max": "54", "mean": "37", "stdev": "7" }, { "name": "nBR", "index": "15", "type": "numeric", "distinct": "2", "missing": "0", "min": "0", "max": "1", "mean": "0", "stdev": "0" }, { "name": "nBT", "index": "16", "type": "numeric", "distinct": "70", "missing": "0", "min": "31", "max": "113", "mean": "74", "stdev": "14" }, { "name": "nC", "index": "17", "type": "numeric", "distinct": "28", "missing": "0", "min": "14", "max": "41", "mean": "28", "stdev": "5" }, { "name": "nCL", "index": "18", "type": "numeric", "distinct": "3", "missing": "0", "min": "0", "max": "2", "mean": "0", "stdev": "0" }, { "name": "nCsp", "index": "19", "type": "numeric", "distinct": "2", "missing": "0", "min": "0", "max": "1", "mean": "0", "stdev": "0" }, { "name": "nCsp2", "index": "20", "type": "numeric", "distinct": "26", "missing": "0", "min": "0", "max": "28", "mean": "16", "stdev": "6" }, { "name": "nCsp3", "index": "21", "type": "numeric", "distinct": "31", "missing": "0", "min": "0", "max": "30", "mean": "13", "stdev": "6" }, { "name": "nDB", "index": "22", "type": "numeric", "distinct": "8", "missing": "0", "min": "0", "max": "7", "mean": "2", "stdev": "1" }, { "name": "nF", "index": "23", "type": "numeric", "distinct": "7", "missing": "0", "min": "0", "max": "8", "mean": "0", "stdev": "1" }, { "name": "nH", "index": "24", "type": "numeric", "distinct": "53", "missing": "0", "min": "10", "max": "69", "mean": "37", "stdev": "10" }, { "name": "nHet", "index": "25", "type": "numeric", "distinct": "13", "missing": "0", "min": "2", "max": "14", "mean": "7", "stdev": "2" }, { "name": "nHM", "index": "26", "type": "numeric", "distinct": "4", "missing": "0", "min": "0", "max": "3", "mean": "1", "stdev": "1" }, { "name": "nI", "index": "27", "type": "numeric", "distinct": "1", "missing": "0", "min": "0", "max": "0", "mean": "0", "stdev": "0" }, { "name": "nN", "index": "28", "type": "numeric", "distinct": "9", "missing": "0", "min": "0", "max": "9", "mean": "3", "stdev": "1" }, { "name": "nO", "index": "29", "type": "numeric", "distinct": "12", "missing": "0", "min": "0", "max": "11", "mean": "3", "stdev": "2" }, { "name": "nP", "index": "30", "type": "numeric", "distinct": "1", "missing": "0", "min": "0", "max": "0", "mean": "0", "stdev": "0" }, { "name": "nS", "index": "31", "type": "numeric", "distinct": "4", "missing": "0", "min": "0", "max": "3", "mean": "0", "stdev": "1" }, { "name": "nSK", "index": "32", "type": "numeric", "distinct": "31", "missing": "0", "min": "18", "max": "50", "mean": "35", "stdev": "6" }, { "name": "nTB", "index": "33", "type": "numeric", "distinct": "2", "missing": "0", "min": "0", "max": "1", "mean": "0", "stdev": "0" }, { "name": "nX", "index": "34", "type": "numeric", "distinct": "7", "missing": "0", "min": "0", "max": "8", "mean": "0", "stdev": "1" }, { "name": "O.", "index": "35", "type": "numeric", "distinct": "105", "missing": "0", "min": "0", "max": "14", "mean": "4", "stdev": "3" }, { "name": "RBF", "index": "36", "type": "numeric", "distinct": "168", "missing": "0", "min": "0", "max": "0", "mean": "0", "stdev": "0" }, { "name": "RBN", "index": "37", "type": "numeric", "distinct": "25", "missing": "0", "min": "1", "max": "27", "mean": "11", "stdev": "5" }, { "name": "SCBO", "index": "38", "type": "numeric", "distinct": "74", "missing": "0", "min": "27", "max": "70", "mean": "47", "stdev": "8" }, { "name": "Se", "index": "39", "type": "numeric", "distinct": "517", "missing": "0", "min": "28", "max": "111", "mean": "72", "stdev": "14" }, { "name": "Si", "index": "40", "type": "numeric", "distinct": "528", "missing": "0", "min": "31", "max": "129", "mean": "82", "stdev": "16" }, { "name": "Sp", "index": "41", "type": "numeric", "distinct": "510", "missing": "0", "min": "22", "max": "68", "mean": "47", "stdev": "8" }, { "name": "Sv", "index": "42", "type": "numeric", "distinct": "525", "missing": "0", "min": "20", "max": "61", "mean": "43", "stdev": "8" }, { "name": "X.", "index": "43", "type": "numeric", "distinct": "37", "missing": "0", "min": "0", "max": "10", "mean": "1", "stdev": "2" } ], "nr_of_issues": 0, "nr_of_downvotes": 0, "nr_of_likes": 0, "nr_of_downloads": 0, "total_downloads": 0, "reach": 0, "reuse": 0, "impact_of_reuse": 0, "reach_of_reuse": 0, "impact": 0 }